已有愈來愈多研究發現,小腦和自閉症及亞斯伯格症之間的關聯。杜耳計畫透過小腦刺激運動,能有效改善亞斯柏格與高功能自閉。



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亞斯柏格的小腦功能行為

此篇研究的論文出處:
http://www.dore.co.uk/research/aspergers.aspx



原文如下:
US National Library of MedicineNational Institutes of Health 美國國家圖書館醫學 國立衛生研究院

Behavioural aspects of cerebellar function in adults with Asperger syndrome.

Source

Behavioural Brain Sciences, School of Psychology, University of Birmingham, UK. e.gowen@bham.ac.uk

Abstract

Aside from social deficits, Asperger and autistic individuals also exhibit motor control abnormalities such as impaired gait, balance, manual dexterity and grip. One brain area that has consistently been reported on autopsy and imaging studies to be abnormal in such individuals is the cerebellum. As the cerebellum controls sensorimotor coordination and lesions here typically cause hypotonia, dysmetria and dyscoordination, we performed a series of quantitative tests aimed at investigating cerebellar function in Asperger individuals. Tests examining visually guided movement (rapid pointing), speeded complex movement (finger tapping, rapid hand turning), muscle tone (catching dropped weight), prediction, coordination and timing (balance, grip force and interval timing) were conducted on 12 Asperger subjects and 12 age and IQ matched controls. In comparison to control subjects, Asperger subject's demonstrated: (i) decreased pointing accuracy and rate, (ii) increased postural instability, and (iii) decreased timing accuracy. IQ was found to co-vary with some parameters of each of these tasks and no further impairments were found on the remaining tests. We suggest that these specific deficits reflect impairment in the ability to integrate sensory input with appropriate motor commands and are consistent with cerebellar dysfunction in Asperger syndrome.


這篇的中文大意是說:

亞斯柏格症及自閉症的個案中, 除了社交困難以外, 也均有運動協調困難的情況, 透過一些解剖及核磁共振的檢查均發現小腦部份有異常狀況.

此研究做了一些實驗, 發現亞斯柏格的個案在智商方面並無異常, 但在運動協調控制上確實有偏弱的情況, 而這些運動協調上的問題, 與小腦功能低落的情況是一致的.